Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pfizer
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Advanced melanoma not responding to 1st line chemotherapy
Histological evidence of melanoma
Measurable disease according to RECIST criteria
ECOG performance status less than or equal to 2
Life expectancy 6 months or more
Normal organ and bone marrow function as defined by hematological and serum chemistry limits
Adequate contraception for females of childbearing potential
You may not be if
Stage IV disease which has previously progressed during interferon treatment.
Restriction of some therapies/medications for a certain timeframe prior to enrollment and during the study including: investigational drugs, high dose corticosteroids, immunotherapy, immunosuppressive medications, radiotherapy and drugs known to prolong QT interval and/or induce Torsades De Pointes
History of uncontrolled seizure disorders
Uncontrolled coagulation disorders.
History or evidence of myocardial ischemia, congestive heart failure or arrythmias requiring treatment in the past 6 months
History of uncontrolled intercurrent or chronic illness
Concurrent malignancies.
Brain metastases.
HIV positive.
Prolonged QTc interval
Uncontrolled intercurrent or chronic illnesses.
Pregnant or lactating women
Clareo Health | Use of 852A in Metastatic Cutaneous Melanoma.
