Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Massachusetts General Hospital
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
DSM-IV diagnostic criteria for bipolar disorder
men or women aged 18-65
a baseline Hamilton-D17 score of \< 10 at screen visit
a baseline YMRS score of \< 10 at screen visit
no acute episodes of depression or mania for the previous 12 weeks.
written informed consent
You may not be if
Subjects with current suicidal ideation
Pregnant women or women of childbearing potential
Serious or unstable medical illness, including cardiovascular, hepatic, renal, respiratory, endocrine, neurologic or hematologic disease; History of seizure disorder, brain injury, any history of known neurological disease (multiple sclerosis, degenerative disease such as ALS, Parkinson disease and any movement disorders, etc)
History or current diagnosis of any of the following DSM-IV psychiatric illnesses: organic mental disorder, schizophrenia, schizoaffective disorder, delusional disorder, psychotic disorders not otherwise specified, major depressive disorder, patients with mood congruent or mood incongruent psychotic features, patients with substance dependence disorders, including alcohol, active within the last 12 months
History of multiple adverse drug reactions
Patients with mood congruent or mood incongruent psychotic features Subjects who are active smokers or who stopped smoking less than 3 months prior to enrollment; Clinical or laboratory evidence of hypothyroidism
Patients who have had an episode of acute depression or mania during the 12 weeks prior to enrollment
Patients who have had electroconvulsive therapy (ECT) within the 6 months preceding enrollment
Patients with physical contraindications to magnetic resonance spectroscopy (ferrous surgical clips, cardiac pacemakers, ferrous prosthesis)
Patients taking any of the following medications: other cholinesterase inhibitors, succinylcholine, neuromuscular blocking agents, cholinergic agonists (e.g., bethanechol), cimetidine, ketoconazole, erythromycin, fluoxetine, paroxetine, and fluvoxamine
Clareo Health | Galantamine-CR and Cognitive Dysfunction in Bipolar Disorder
