Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Beth Israel Deaconess Medical Center
With
AstraZeneca
This is a three-month study where baseline information is collected at the first visit and then each patient is started on treatment with testosterone supplementation and either anastrozole or placebo. Lab tests, seizure frequency, sexual function and mood will be monitored on a monthly basis.
Age
18–50
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Subject must be a male between the ages of 18 and 50 years.
Subject must have localization-related epilepsy with complex partial and/or secondary generalized seizures.
Subject will meet criteria for hypogonadism (abnormally low bioactive testosterone levels and abnormally low scores on questionnaires of reproductive and sexual function).
Subject will have had a normal urogenital and rectal/prostate exam during the year prior to entry.
Subject will have had documentation of therapeutic range serum AED levels, a normal CBC, and hepatic enzyme (ALT,AST, alkaline phosphatase) levels that are less than twofold elevated during the 6 months prior to entry.
You may not be if
Subject that has taken hormones, major tranquilizers or antidepressants in the three months prior to entry.
