Efficacy, Safety, and Tolerability of Darifenacin in Patients Aged > 65 Years With Overactive Bladder

Exclusion Criteria

• •A total daily urinary volume \> 3000 ml or a mean volume voided per micturition of \> 300 ml as verified in the micturition diary before randomization
• •Post-void residual (PVR) urinary volume \> 100 ml
• •Clinically significant stress urinary incontinence as determined by the investigator
• •Clinically significant bladder outlet obstruction as determined by the investigator
• •Concomitant diseases in which the use of anticholinergic drugs is contraindicated, e.g. urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, myasthenia gravis, severe hepatic impairment (Child Pugh B and C), severe ulcerative colitis, toxic megacolon.