Access II - Trial of Warfarin to Prevent Malfunction of Haemodialysis Catheters

Exclusion Criteria

• •Major bleed within last 3 months
• •Platelet count less than 50 x 10 9/L or current coagulopathy (most recent INR \> 1.5, not due to warfarin)
• •Active peptic ulcer disease
• •Anticipated need for invasive intervention within next 2 weeks
• •Taking warfarin for an indication other than access prophylaxis
• •Allergic to, or intolerant of, warfarin
• •Pregnant
• •Woman of child-bearing age who has not agreed to use an adequate method of birth control for the duration of the study
• •Catheter likely needed for 2 weeks or less
• •Patient previously took part in the study
• •Patient has known aortic aneurysm of 6cm or greater
• •Patients nephrologist has refused consent
• •Patient has refused consent