Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Dana-Farber Cancer Institute
With
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center
Massachusetts General Hospital
In the week before the patients first dose of chemotherapy they will receive a C11 methionine PET scan which takes about 90 minutes. C11 methionine is a radioactively labeled amino acid that is given to the patient intravenously.
Eighteen to twenty days after the patients first dose of docetaxel chemotherapy, they will have another C11 methionine PET scan which is identical to the first scan.
At the end of three cycles of docetaxel chemotherapy (about 2 and 1/2 months on study) another C11 methionine PET scan will be done.
The PET scans will show how well the tumor is taking up methionine.
Age
18–any
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Metastatic hormone-refractory prostate cancer patients who are planned to begin every 3-week docetaxel chemotherapy
Progression after androgen deprivation therapy
Serum testosterone \< 50ng/ml
18 years of age or older
You may not be if
Prior taxane therapy
Clareo Health | Evaluation of the Effects of Chemotherapy on the Uptake and Retention of Carbon 11 Methionine in Prostate Cancer Patients
