Study of Peri-Operative Docetaxel Plus Laparoscopic Radical Prostatectomy in Prostate Cancer Patients

Inclusion Criteria

• •Patients older than 18 years and less than 70 years
• •Histologically-proven Gleason 7 adenocarcinoma of the prostate
• •pT2a or pT2b disease based on biopsies of the prostate
• •More than 2/3 of positive biopsies or 15 ≤ serum PSA \<20
• •No previous carcinoma, except basal-cell carcinoma of the skin
• •Adequate renal function: measured or calculated creatinine clearance\> 60 ml/min
• •Absolute granulocyte count ≥ 1,500/mm3, platelets ≥ 100,000 mm3, bilirubin ≤ 1.5 fold the upper normal value
• •Signed informed consent.