Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1

Exclusion Criteria

• •Meets criteria for current abuse or dependence for any alcohol or illicit substance within the past month
• •History of hypersensitivity to bupropion or the nicotine transdermal patch (NTP)
• •Current diagnosis of a serious documented medical disorder that would make bupropion treatment risky OR results of psychiatric/medical screening that suggest a reason for concern (e.g., a history of severe heart, liver, or kidney disease or diabetes mellitus)
• •Currently taking monoamine oxidase inhibitors or bupropion (Zyban or Wellbutrin)
• •Currently taking diabetes mellitus medications, St. John's Wort, appetite suppressants, ephedrine-containing medications, theophylline, clonidine, reserpine, methyldopa, or anti-anginal medications (e.g., beta-blockers, calcium channel blockers, nitroglycerin preparations)
• •History of schizoaffective disorder and not stabilized on a mood stabilizer (e.g., lithium, valproate, carbamazepine)