Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pharmacyclics LLC.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
≥ 18 years old
Histologically or cytologically confirmed diagnosis of cancer (i.e., Unresectable locally advanced or metastatic non-small-cell lung carcinoma (NSCLC) that had progressed during or after one or more chemotherapy regimens; Metastatic breast cancer; Hormone-refractory prostate cancer; Recurrent or refractory ovarian cancer; Sarcoma)
ECOG performance status score either 0 or 1
Willing and able to provide written informed consent
You may not be if
Laboratory Values of:
Absolute neutrophil count \< 2000/µL
Platelet count \< 100,00/µL
AST or ALT \> 1.5 x the upper limit of normal
Alkaline phosphatase \> 5 x the upper limit of normal
Bilirubin \> ULN
Creatinine \> 2.0 mg/dL
and
Peripheral neuropathy NCI CTC Grade 3 or higher
Chemotherapy, radiation therapy, immunotherapy, or systemic biologic
anticancer therapy within 21 days before beginning study treatment
Known history of brain metastases or spinal cord compression
Uncontrolled hypertension
Myocardial infarction within 6 months before beginning study treatment
