Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
GERCOR - Multidisciplinary Oncology Cooperative Group
OBJECTIVES: Primary * Determine the maximum tolerated dose of docetaxel and oxaliplatin in patients with stage III or IV ovarian epithelial cancer. * Determine the toxicity of this regimen in these patients. Secondary * Determine the tolerance profile of patients treated with this regimen. * Determine a recommended phase III dose of this regimen in these patients. * Determine the efficacy of this regimen, in terms of objective response rate and radiological and biological response rate (CA 125), in these patients. * Determine the complete pathological response in patients treated with this regimen as first-line therapy. * Determine the duration of the objective response in patients treated with this regimen. * Determine the time to progression in patients treated with this regimen. OUTLINE: This is a dose-escalation, multicenter study. Patients receive docetaxel IV over 1 hour and oxaliplatin IV over 2 hours on day 1. Treatment repeats every 3 weeks for 6 courses in the absence of disease progression or unacceptable toxicity. Patients are followed monthly for 3 months. PROJECTED ACCRUAL: A total of 30-39 patients will be accrued for this study.
Age
18–75
Sex
FEMALE
Healthy volunteers
Not accepted
