Objectives: to study potential structural and functional abnormalities in patients with an inherited form of epilepsy.
Study Population: Patients with autosomal dominant partial epilepsy with auditory features, a newly described syndrome, asymptomatic family members who are gene carriers, and unaffected family members, and normal volunteers.
Design: magnetic resonance imaging, electroencephalography, and magnetoencephalography.
Outcome measures: detection of structural lesions; regional activation patterns on fMRI.