Normal left ventricular ejection fraction (LVEF) as determined by MUGA (Multiple Gated Acquisition) scan or echocardiogram
HER-2/neu status is determined by a FISH (Fluorescence in situ hybridization) test. \[FISH (+) is HER-2/neu (+)\]
If female of childbearing potential, pregnancy test is negative
If premenopausal and not surgically sterilized, the patient agrees to use effective birth control method for the duration of the study
Informed consent has been obtained
You may not be if
Non-confirmed infiltrating adenocarcinoma breast cancer
Evidence of metastasis
Previous chemotherapy using the drugs proposed in this study, specifically Herceptin®, Taxotere®, and/or Carboplatin
Prior radiation to the involved breast
Recent breast cancer drug therapy within last 5 years of any form
History of allergy to polysorbate or castor oil
Ongoing active infection
Concurrent life-limiting disease with a life expectancy of less than one year
Past or current history of other malignancy within the past 5 years which could affect the diagnosis or assessment of breast cancer, except for curatively treated non-melanoma skin cancer and/or in situ carcinoma of the cervix
Pregnancy, nursing, fertile women who do not use birth control device
Inability to give informed consent
Patients with pre-existing peripheral neuropathy \> grade 2
Clareo Health | Docetaxel and Carboplatin With or Without Trastuzumab Before Surgery in Treating Women With Locally Advanced Breast Cancer
