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Keep this study
Lead
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
This study will evaluate the utility of the endometrial biopsy as a tool for the routine evaluation of the luteal phase of women presenting for infertility evaluation. The study will establish whether the mid-luteal or late-luteal phase is the most appropriate time to perform an endometrial biopsy. The study will be conducted through the multi-center Reproductive Medicine Network.
Women with a history of infertility will be age matched to fertile women (controls). Women will be randomized either to the mid-luteal phase (7 to 8 days post-ovulation) endometrial biopsy group or to the late-luteal phase (12 to 13 days post-ovulation) endometrial biopsy group. Endometrial specimens will be evaluated histologically by a "blinded" pathologist.
Age
25–39
Sex
FEMALE
Healthy volunteers
Accepted
You may be eligible if
No history of involuntary primary or secondary infertility
Willingness to discontinue hormonal contraceptives for 1 month prior to and through the duration of the study
At least 1 child delivered within 24 months prior to study entry
Most recent pregnancy resulting in a live birth (no interim spontaneous abortions)
Tubal ligation within 24 months of study entry is acceptable if all other criteria are met
History of primary or secondary infertility for a period of at least 12 months
No hormonal treatments in the month preceding study entry
No history of tubal ligation
Clareo Health | Endometrial Biopsy in Infertile Patients
