Therapy for Depression With Co-occurring Panic or Anxiety Symptoms

Exclusion Criteria

• •History of manic episode(s). Patients who have had hypomanic episodes in the past will be accepted into the study, provided they meet other admission criteria and are not presenting in a current hypomanic or mixed episode.
• •History of schizophrenia or schizoaffective disorder.
• •Organic affective syndrome.
• •Unspecified functional psychosis.
• •Anorexia nervosa or bulimia nervosa. Patients meeting criteria for an eating disorder not otherwise specified will not be excluded.
• •Chronic drug or alcohol abuse/dependence within the past 2 years. Patients with abuse related to episodes will not be excluded.
• •DSM-IV criteria for borderline or antisocial personality disorder. Patients who meet criteria for other Axis II disorders will not be excluded.
• •Inpatient treatment due to suicide risk or psychotic symptoms.
• •Index episode secondary to the effect of medically prescribed drugs.
• •Significant or untreated medical illness, including cardiovascular disorder, renal or liver disease, epilepsy, untreated hypertension, or unstabilized endocrine disease.
• •Medical illness that would interfere with the best treatment strategy for the potential participant.
• •Current treatment with an antidepressant. Patients on a stable dose of anxiolytics for at least 3 months prior to study participation who are able to maintain this dosage throughout the study will not be excluded.
• •Pregnant and breast-feeding women will be accepted into the study, but will not be prescribed adjunctive medications.