Study of T900607-Sodium in Previously Treated Patients With Ovarian Cancer.

Inclusion Criteria

• •Histologically or cytologically confirmed diagnosis of ovarian cancer
• •Subjects must have received 1-2 regimens of prior chemotherapy (with one containing paclitaxel)
• •At least 18 years of age
• •Bidimensionally measurable disease amenable to CT scanning. At least one lesion must be least 1 X 1 cm in size.
• •Karnofsky performance status of at least 70%
• •Estimated life expectancy of at least 12 weeks
• •Females of childbearing potential must have a negative pregnancy test and agree to use an effective contraceptive
• •Subject must be able to comply with study procedures and follow-up examinations.
• •Signed written informed consent
• •Lab Values (obtained ≤ 7 days prior to study enrollment):
• •ANC at least 1.5x10e9/L,
• •Platelet count at least 100x10e9/L,
• •Hemoglobin at least 8.5 g/dL,
• •Creatinine within 2 times upper limit of normal
• •AST and ALT within 3 times upper limit of normal
• •Bilirubin within 1.5 times upper limit of normal
• •Albumin great than 2.5 g/dL
• •INR \< 1.5 for subjects without anticoagulants