The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Inclusion Criteria

• •Patients with cystic fibrosis who have a defined mutation in CFTR (e.g., any of the known variants of the CFTR gene, such as the delta F508 allele) born in the state of Wisconsin since 1985 or otherwise followed by the cystic fibrosis centers at the Medical College of Wisconsin or University of Wisconsin-Madison.
• •Patients will have been tested or will be tested for the CFTR gene under another protocol (96-H-0100).
• •Patients may be colonized with P. aeruginosa or other organisms (e.g., Burkholderia cepacia).
• •The age range of NIH participants in this study is from 9 to 80 years old.