Prophylactic Use of Filgrastim SD/01 in Patients With Hodgkin's Disease Receiving ABVD Chemotherapy

You may be eligible if

• INCLUSION:
• Previously untreated Hodgkin's disease patients who are scheduled to receive standard ABVD chemo.
• Histologically proven diagnosis of Hodgkin's disease of any type.
• Bidimensionally measurable disease.
• Signed informed consent.
• Age \>/= 16 yrs.
• Adequate bone marrow reserve (ANC\>1000/uL, Platelet \>100,000/uL.
• LVEF\>/=50% by MUGA scan or echocardiogram.
• Serum creatinine \<2mg/dL; serum bilirubin\<2mg/dL.
• EXCLUSION:
• HIV positive.
• Pregnant women and those of child bearing age who are not using adequate contraception.
• Prior chemotherapy.
• Severe pulmonary disease including COPD and asthma.
• History of prior sensitivity to E.coli derived products.