St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder.

Exclusion Criteria

• •Primary diagnosis of major depression, dysthymia, panic disorder, social phobia, schizophrenia, schizo-affective disorder, bipolar disorder, or PTSD
• •Substance abuse or dependence in the past 6 months
• •Vascular dementia or primary degenerative dementia of the Alzheimer's type
• •Treatment with MAOIs, TCAs, SSRIs, venlafaxine, nefazodone, remeron, citalopram, or bupropion within 14 days of first visit.
• •Fluoxetine within 5 weeks of first visit.
• •Failure to respond to at least two adequate antidepressant trials for obsessive compulsive disorder
• •Investigational drugs within 30 days of baseline
• •Known allergy or hypersensitivity to St. John's Wort
• •Currently in behavior therapy for obsessive compulsive disorder
• •ALL INQUIRIES WILL UNDERGO A PHONE SCREENING TO DETERMINE WHETHER THEY MEET ELIGIBLITY REQUIREMENTS.