Naltrexone for Relapse Prevention

Exclusion Criteria

• •Meets criteria for dependence on a psychoactive substance other than alcohol and nicotine and/or cannabis.
• •Prior history of opioid dependence.
• •Regular use of psychoactive drugs including anxiolytics and antidepressants.
• •Prior treatment with naltrexone.
• •Current use of disulfiram.
• •Psychotic or otherwise severely psychiatrically disabled (e.g., suicidal, current mania).
• •Significant underlying medical conditions such as hepatic, cerebral, renal, thyroid, or cardiac disease.
• •Abstinent longer than 28 days prior to randomization.